Retinitis Pigmentosa: An Overview
Retinitis Pigmentosa (RP) is a genetic disease that encompasses a spectrum of hereditary conditions caused by shared physiological processes that lead to retinal degeneration (1). In RP, genes that encode proteins responsible for photoreceptor and retinal pigment epithelium function get mutated. More than 100 genetic mutations have been implicated in RP, causing a loss of rod and cone photoreceptors in the retina through apoptosis (1). Initially, rod photoreceptors are predominantly affected, followed later by degeneration of cones (rod-cone dystrophy) (2).