Reactive Arthritis (RA), formerly known as Reiter’s Syndrome, refers to non-septic joint inflammation that develops in reaction to an infection in another part of the body. RA is often characterized by a classic triad of symptoms: inflammation of multiple asymmetric joints usually in the lower limbs, inflammation of the eyes in the form of conjunctivitis or uveitis and urethritis in men or cervicitis in women. These three symptoms may occur separately, all at once or not at all.

Herpes Zoster (HZ) is a viral infection of an individual nerve and its corresponding dermatome following reactivation of latent varicella zoster virus (VZV). Approximately 1 in 4 people will develop herpes zoster in their lifetime, with incidence and severity increasing with age. Other important risk factors for VZV include an immunocompromised state, certain comorbidities, psychological factors and female sex. This article presents a case of Herpes Zoster Ophthalmicus with ocular involvement in an immunocompromised 64-year-old male patient.