Delayed Spontaneous Macular Hole Closure: Insights into Basic Pathophysiology
Idiopathic macular holes (MHs) are most prevalent in the sixth and seventh decade of life with approximately two-thirds of patients being female, and can significantly impact patients’ quality of life. Although the aetiology is unknown, a range of risk factors have been proposed including; myopia, retinal detachment, hypertension and diabetic retinopathy.