Despite being a rare cancer overall, uveal melanoma is the most common primary intraocular malignancy in adults. Split into different subtypes, the most common type of uveal melanoma is choroidal melanoma (90%), followed by ciliary body and iris melanoma. Despite being a melanoma, uveal melanomas differ greatly from the more common cutaneous melanomas in areas including physiology, genetics, and management. This article will provide a brief overview of uveal melanoma, as well as identify some key differences from cutaneous melanomas.